Article
Metallothionein 1A polymorphisms may influence urine uric acid and N-acetyl-beta-D-glucosaminidase (NAG) excretion in chronic lead-exposed workers.
Toxicology - 5 Apr 2013
Yang Chen-Cheng, Chen Hsin-I, Chiu Yu-Wen, Tsai Chih-Hung, Chuang Hung-Yi
Abstract excerpt
Lead is a renal toxin, and susceptibility to lead varies between individuals. Metallothionein (MT) is known for its metal scavenging role. The aim of the study was to investigate the association of blood lead levels, urinary uric acid (UA) and N-acetyl-beta-d-glucosaminidase (NAG) in chronic occupational lead-exposed workers, and to study whether the association was influenced by MT1A gene polymorphisms. In this...
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