Article
Phenotypic heterogeneity influences the behavior of rat aortic smooth muscle cells in collagen lattice.
Experimental cell research - 10 Dec 2005
Orlandi Augusto, Ferlosio Amedeo, Gabbiani Giulio, Spagnoli Luigi Giusto, Ehrlich Paul H
Abstract excerpt
Phenotypic modulation of vascular smooth muscle cells (SMCs) in atherosclerosis and restenosis involves responses to the surrounding microenvironment. SMCs obtained by enzymatic digestion from tunica media of newborn, young adult (YA) and old rats and from the thickened intima (TI) and underlying media of young adult rat aortas 15 days after ballooning were entrapped in floating populated collagen lattice (PCL)....
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