Article
Localization and function of the connexin 43 gap-junction protein in normal and various oncogene-expressing rat liver epithelial cells.
Molecular carcinogenesis - 1 Aug 1996
de Feijter A W, Matesic D F, Ruch R J, Guan X, Chang C C, Trosko J E
Abstract excerpt
Clones of rat liver epithelial cells genotypically altered by mutation or by a variety of oncogenes were analyzed by microinjection-dye transfer, immunofluorescence confocal microscopy, and western blotting to determine at what level and to what degree these transformations disrupted gap-junction...
Topics
- Animals
- Blotting, Western
- Cell Communication
- Cell Transformation, Neoplastic
- Cells, Cultured
- Connexin 43
- Epithelial Cells
- Epithelium
- Gap Junctions
- Gene Expression
- Isoquinolines
- Liver
- Mice
- Microinjections
- Microscopy, Phase-Contrast