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Article

Manipulating the<i>Plasmodium</i>Genome

1 Jan 2005

Abstract excerpt

Genome manipulation, the primary tool for assigning function to sequence, will be essential for understanding Plasmodium biology and malaria pathogenesis in molecular terms. The first success in transfecting Plasmodium was reported almost ten years ago. Gene-targeting studies have since flourished, as Plasmodium is haploid and integrates DNA only by homologous recombination. These studies have shed new light on...

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PMID: 15580779
DOI: 10.21775/cimb.007.039

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