Article
The basic domain of ATH5 mediates neuron-specific promoter activity during retina development.
Molecular and cellular biology - 1 Nov 2005
Skowronska-Krawczyk Dorota, Matter-Sadzinski Lidia, Ballivet Marc, Matter Jean-Marc
Abstract excerpt
In the developing retina, the gene encoding the beta3 subunit of the neuronal nicotinic receptor, a specific marker of retinal ganglion cells, is under the direct control of the atonal homolog 5 (ATH5) basic helix-loop-helix (bHLH) transcription factor. Although quite short (143 bp in length), the beta3 promoter has the remarkable capacity to discriminate between ATH5 and the other neuronal bHLH proteins...
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