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Article

Smooth muscle-specific genes are differentially sensitive to inhibition by Elk-1.

Molecular and cellular biology - 1 Nov 2005

Zhou Jiliang, Hu Guoqing, Herring B Paul

Abstract excerpt

Understanding the mechanism of smooth muscle cell (SMC) differentiation will provide the foundation for elucidating SMC-related diseases, such as atherosclerosis, restenosis, and asthma. In the current study, overexpression of Elk-1 in SMCs down-regulated expression of several endogenous smooth muscle-restricted proteins, including telokin, SM22alpha, and smooth muscle alpha-actin. In contrast, down-regulation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16260603
DOI: 10.1128/MCB.25.22.9874-9885.2005
PMCID: PMC1280275

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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