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Article

Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation.

Carcinogenesis - 1 Jun 1992

Chang W P, Little J B

Abstract excerpt

Residual damage manifested as reduced cloning efficiency was observed in many of the cloned progeny of Chinese hamster ovary (CHO) cells and human carcinoma SQ-20B cells surviving X-irradiation. This stable phenotype, which we have termed delayed reproductive death, persisted for greater than 50 generations of cell replication post-irradiation. Clones showing this phenotype were aneuploid, and formed colonies...

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Identifiers

PMID: 1600612
DOI: 10.1093/carcin/13.6.923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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