Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation.

doi:10.1093/carcin/13.6.923

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Article

Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation.

Carcinogenesis - 1 Jun 1992

Chang W P, Little J B

Abstract excerpt

Residual damage manifested as reduced cloning efficiency was observed in many of the cloned progeny of Chinese hamster ovary (CHO) cells and human carcinoma SQ-20B cells surviving X-irradiation. This stable phenotype, which we have termed delayed reproductive death, persisted for greater than 50...

Topics

Animals
CHO Cells
Carcinoma, Squamous Cell
Cell Survival
Clone Cells
Colony-Forming Units Assay
Cricetinae
Humans
Laryngeal Neoplasms
Phenotype
Tumor Cells, Cultured

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