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Article

Tryptophan hydroxylase polymorphism is associated with age of onset of alcoholism related behaviors.

Alcohol (Fayetteville, N.Y.) - 1 May 2005

Chung In-Won, Kim Heon, Sribney William, Hong Joo-Bong, Lee Chul-Ho, Lee Kyu-Young, Nan Hong-Mei, Kim Yong-Sik, Manowitz Paul

Abstract excerpt

The purpose of this study was to explore the association of a tryptophan hydroxylase gene polymorphism (TPH1 A218C) with the age of alcoholism onset in a Korean population. The genotype and allele frequencies of TPH1 were investigated in 182 male hospitalized patients who met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria for alcohol dependence....

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Source

Identifiers

PMID: 16257348
DOI: 10.1016/j.alcohol.2005.06.004

Genes

TPH1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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