Article
[The 444G/A and -1021 C/T polymorphisms of the dopamine-beta-hydroxylase gene modulate the trajectory of alcohol dependence development].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2015
Kibitov A O, Voskoboeva E Yu, Chuprova N A
Abstract excerpt
AIM: To study the influence of 444 G/A (rs 1108580) and -1021 C/T (rs 1611115) polymorphisms of the dopamine beta-hydroxylase (DBH) gene on clinical parameters of the trajectory of alcohol dependence. MATERIAL AND METHODS: Authors studied 548 male inpatients, of Slavic ethnicity, with ICD-10 diagnosis of «alcohol dependence» (F-10.2). RESULTS: The effects of DBH * 444 G/A on the rate of formation of alcohol...
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