Article
Association between smoking habits and tryptophan hydroxylase gene C218A polymorphism among the Japanese population.
Journal of epidemiology - 1 May 2004
Mizuno Shoichi, Ito Hidemi, Hamajima Nobuyuki, Tamakoshi Akiko, Hirose Kaoru, Tajima Kazuo
Abstract excerpt
BACKGROUND: Genetic polymorphisms have proposed a new insight in smoking behavior. Genes in serotonin system are one of the candidates because of serotonin's role in mood regulation. A polymorphism C218A in intron 7 of the tryptophan hydroxylase (TPH) gene has been hypothesized in relation to smoking predisposition. METHODS: We examined the association on two Japanese populations: one was from the first-visit...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
