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Article

Association of the tryptophan hydroxylase gene with smoking initiation but not progression to nicotine dependence.

American journal of medical genetics - 8 Jul 2001

Sullivan P F, Jiang Y, Neale M C, Kendler K S, Straub R E

Abstract excerpt

We investigated the association between two markers in the seventh intron of the tryptophan hydroxylase gene (TPH C218A and C779A) in a population-based case control study of 780 genotyped subjects. As in prior studies, the two markers were in strong linkage disequilibrium. The phenotypes we studied were smoking initiation and progression to nicotine dependence. Allele, genotype, and estimated haplotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11449402
DOI: 10.1002/ajmg.1433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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