Article
No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria.
Alcoholism, clinical and experimental research - 1 Jun 2001
Anghelescu I, Germeyer S, Müller M J, Klawe C, Singer P, Dahmen N, Wetzel H, Himmerich H, Szegedi A
Abstract excerpt
BACKGROUND: The presence of the A1 allele of the dopamine D2 receptor TaqI restriction fragment length polymorphism has been reported to be associated with an earlier age of onset of alcohol dependence as a marker for severity. METHODS: We tested this hypothesis with special regard to the definition of the age of onset of alcoholism in 243 patients with alcohol dependence, according to DSM-IV criteria assessed by...
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