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Article

Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.

Toxicology letters - 10 Apr 2006

Talaska Glenn, Ginsburg David, LaDow Kathy, Puga Alvaro, Dalton Timothy, Warshawsky David

Abstract excerpt

UNLABELLED: Studies of the impact of phase 1 enzyme polymorphisms on genetic damage have yielded mixed results. We studied how genetic damage would be altered when specific genes were ablated under low dose conditions. METHODS: Knockouts (KO) were generated from c57bl6/J mice with mutations in Cyp1a2 or Ahr receptor that eliminated gene product function. Animals were treated topically with either 4-aminobiphenyl...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16256281
DOI: 10.1016/j.toxlet.2005.09.020

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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