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Epigenetic regulation in development: is the mouse a good model for the human?

5 Jun 2018

Abstract excerpt

BACKGROUND: Over the past few years, advances in molecular technologies have allowed unprecedented mapping of epigenetic modifications in gametes and during early embryonic development. This work is allowing a detailed genomic analysis, which for the first time can answer long-standing questions about epigenetic regulation and reprogramming, and highlights differences between mouse and human, the implications of...

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PMID: 29992283
DOI: 10.1093/humupd/dmy021

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