Article
Advances in mouse genetics for the study of human disease.
Human molecular genetics - 1 Oct 2021
Brown Steve D M
Abstract excerpt
The mouse is the pre-eminent model organism for studies of mammalian gene function and has provided an extraordinarily rich range of insights into basic genetic mechanisms and biological systems. Over several decades, the characterization of mouse mutants has illuminated the relationship between gene and phenotype, providing transformational insights into the genetic bases of disease. However, if we are to...
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