Article
Epigenetics.
Advances in experimental medicine and biology - 1 Jan 2024
Jain Rajan, Epstein Jonathan A
Abstract excerpt
Epigenetics is the study of heritable changes to the genome and gene expression patterns that are not caused by direct changes to the DNA sequence. Examples of these changes include posttranslational modifications to DNA-bound histone proteins, DNA methylation, and remodeling of nuclear architecture. Collectively, epigenetic changes provide a layer of regulation that affects transcriptional activity of genes...
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