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Article

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.

FEBS letters - 7 Nov 2005

Kim Young Ho, Sung Ki Sa, Lee Sook-Jeong, Kim Yong-Ou, Choi Cheol Yong, Kim Yongsok

Abstract excerpt

The modification of homeodomain-interacting protein kinase 2 (HIPK2) by small ubiquitin-like modifier 1 (SUMO-1) plays an important role in its targeting into the promyelocytic leukemia body, as well as in its differential interaction with binding partner, but the desumoylation of HIPK2 by SUMO-s...

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Source

Identifiers

PMID: 16253240
DOI: 10.1016/j.febslet.2005.10.010

Genes

SENP1
HIPK2
NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16253240-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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