Article
Vitamin D receptor gene haplotype is associated with body height and bone size.
The Journal of clinical endocrinology and metabolism - 1 Apr 2007
Fang Yue, van Meurs Joyce B J, Rivadeneira Fernando, van Schoor Natasja M, van Leeuwen Johannes P T, Lips Paul, Pols Huibert A P, Uitterlinden André G
Abstract excerpt
CONTEXT: Adult stature is a complex genetic trait. The vitamin D endocrine system has pleiotropic effects on several physiological processes, especially on skeletal metabolism. We recently identified promoter and 3'-untranslated region (UTR) haplotype alleles that influence vitamin D receptor (VDR) mRNA expression. OBJECTIVE: We studied whether VDR gene variants contribute to the genetic variation in height....
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