Article
Vitamin D receptor gene haplotypes and polymorphisms and risk of breast cancer: a nested case-control study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2012
Engel Lawrence S, Orlow Irene, Sima Camelia S, Satagopan Jaya, Mujumdar Urvi, Roy Pampa, Yoo Sarah, Sandler Dale P, Alavanja Michael C
Abstract excerpt
BACKGROUND: Observational and experimental studies suggest that vitamin D may influence breast cancer etiology. Most known effects of vitamin D are mediated via the vitamin D receptor (VDR). Few polymorphisms in the VDR gene have been well studied in relation to breast cancer risk and results have been inconsistent. METHODS: We investigated VDR polymorphisms and haplotypes in relation to breast cancer risk by...
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