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Article

The apolipoprotein E gene promoter (-219G/T) polymorphism determines insulin sensitivity in response to dietary fat in healthy young adults.

The Journal of nutrition - 1 Nov 2005

Moreno Juan Antonio, Pérez-Jiménez Francisco, Marín Carmen, Pérez-Martínez Pablo, Moreno Rafael, Gómez Purificación, Jiménez-Gómez Yolanda, Paniagua Juan Antonio, Lairon Denis, López-Miranda José

Abstract excerpt

Insulin sensitivity (IS) is determined by genetic and environmental factors, including diet. The apoE gene promoter -219G/T polymorphism is associated with coronary heart disease and increased postprandial triacylglycerol-rich lipoprotein concentration, circumstances related to insulin resistance. Thus, our aim was to determine whether this polymorphism modified the IS response to dietary fat in healthy young...

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PMID: 16251607
DOI: 10.1093/jn/135.11.2535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The apolipoprotein E gene promoter (-219G/T) polymorphism determines insulin sensitivity in response to dietary fat in healthy young adults.PMID 16251607Read ↗

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