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Article

Variants in the APOC3 promoter insulin responsive element modulate insulin secretion and lipids in middle-aged men.

Biochimica et biophysica acta - 17 Apr 2003

Waterworth D M, Talmud P J, Luan J, Flavell D M, Byrne C D, Humphries S E, Wareham N J

Abstract excerpt

Variation in the insulin responsive element (IRE) of the APOC3 promoter has been shown to be associated with insulin and glucose concentrations after an oral glucose tolerance test (OGTT) in young healthy men. We evaluated two variants in the IRE (-455T>C and -482C>T) in the Ely study, a prospect...

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Source

Identifiers

PMID: 12697301
DOI: 10.1016/s0925-4439(03)00021-8

Genes

APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12697301-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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