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Article

Calibrating a coalescent simulation of human genome sequence variation.

Genome research - 1 Nov 2005

Schaffner Stephen F, Foo Catherine, Gabriel Stacey, Reich David, Daly Mark J, Altshuler David

Abstract excerpt

Population genetic models play an important role in human genetic research, connecting empirical observations about sequence variation with hypotheses about underlying historical and biological causes. More specifically, models are used to compare empirical measures of sequence variation, linkage disequilibrium (LD), and selection to expectations under a "null" distribution. In the absence of detailed information...

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Identifiers

PMID: 16251467
DOI: 10.1101/gr.3709305
PMCID: PMC1310645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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