Article
Population genetic inference from genomic sequence variation.
Genome research - 1 Mar 2010
Pool John E, Hellmann Ines, Jensen Jeffrey D, Nielsen Rasmus
Abstract excerpt
Population genetics has evolved from a theory-driven field with little empirical data into a data-driven discipline in which genome-scale data sets test the limits of available models and computational analysis methods. In humans and a few model organisms, analyses of whole-genome sequence polymorphism data are currently under way. And in light of the falling costs of next-generation sequencing technologies, such...
Topics
- Base Sequence
- Chromosome Mapping
- Genes
- Genetic Variation
- Genetics, Population
- Genome
- Humans
- Polymorphism, Genetic
- Population Groups
- Selection, Genetic