Article

Leveraging distant relatedness to quantify human mutation and gene conversion rates

2015-06-16

Abstract excerpt

The rate at which human genomes mutate is a central biological parameter that has many implications for our ability to understand demographic and evolutionary phenomena. We present a method for inferring mutation and gene conversion rates using the number of sequence differences observed in identical-by-descent (IBD) segments together with a reconstructed model of recent population size history. This approach is r...

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Literature Corpus work: a8aef476-93f0-5e60-a995-e4b435964ff7
DOI: 10.1101/020776

Open publication

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