Article
Investigation of the mechanism of resistance to third-generation cephalosporins by class C beta-lactamases by using chemical complementation.
Chembiochem : a European journal of chemical biology - 1 Nov 2005
Carter Brian T, Lin Hening, Goldberg Shalom D, Althoff Eric A, Raushel Jessica, Cornish Virginia W
Abstract excerpt
The widespread use of antibiotics to treat bacterial infections has led to the continuing challenge of antibiotic resistance. For beta-lactam antibiotics, the most common form of resistance is the expression of beta-lactamase enzymes, which inactivate the antibiotics by cleavage of the beta-lacta...
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