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Article

Fluorescein-labeled beta-lactamase mutant for high-throughput screening of bacterial beta-lactamases against beta-lactam antibiotics.

Analytical chemistry - 15 Aug 2005

Chan Pak-Ho, Chan Kwok-Chu, Liu Hong-Bing, Chung Wai-Hong, Leung Yun-Chung, Wong Kwok-Yin

Abstract excerpt

The increasing emergence of new bacterial beta-lactamases that can efficiently hydrolyze beta-lactam antibiotics to clinically inactive carboxylic acids has created an intractable problem in the treatment of bacterial infections, and it is highly desirable to develop a useful tool that can rapidl...

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PMID: 16097768
DOI: 10.1021/ac0502605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16097768-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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