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Article

p38 MAP kinase regulates the expression of XMyf5 and affects distinct myogenic programs during Xenopus development.

Developmental biology - 1 Dec 2005

Keren Aviad, Bengal Eyal, Frank Dale

Abstract excerpt

The p38 MAPK signaling pathway is essential for skeletal muscle differentiation in tissue culture models. We demonstrate a novel role for p38 MAPK in myogenesis during early Xenopus laevis development. Interfering with p38 MAPK causes distinct defects in myogenesis. The initial expression of Myf5 is selectively blocked, while expression of MyoD is unaffected. Expression of a subset of muscle structural genes is...

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Identifiers

PMID: 16248994
DOI: 10.1016/j.ydbio.2005.09.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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