Article
Amplification of<i>Plasmodium falciparum</i>Multidrug Resistance Gene 1 in Isolates from Gabon
25 Oct 2005
Abstract excerpt
The study of molecular markers of drug resistance is particularly important in surveillance studies of drugs, such as mefloquine, that still retain efficacy in sub-Saharan Africa yet have encountered resistance elsewhere. In a recent study in Thailand, we identified amplification of the Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) as being the most important predictor of in vitro drug resistance and...
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