Article
Persistence of distinct HIV-1 populations in blood monocytes and naive and memory CD4 T cells during prolonged suppressive HAART.
AIDS (London, England) - 4 Nov 2005
Delobel Pierre, Sandres-Sauné Karine, Cazabat Michelle, L'Faqihi Fatima-Ezzahra, Aquilina Christian, Obadia Martine, Pasquier Christophe, Marchou Bruno, Massip Patrice, Izopet Jacques
Abstract excerpt
OBJECTIVE: Reservoirs of HIV-1 are a major obstacle to virus eradication. There is therefore a need to clearly understand the molecular nature of the virus populations that persist in patients with sustained suppression of plasma viraemia on highly active antiretroviral therapy (HAART). DESIGN: We performed a detailed analysis of the genotypes of HIV-1 quasispecies isolated from highly purified blood cell types...
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