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Article

Endolymphatic delivery of IL2 in patients with melanoma and lymphoma.

Biotherapy (Dordrecht, Netherlands) - 1 Jan 1992

Galvani D W, Walton S, Davies J M, Owen R R, Carr R, Cawley J C, Sells R A

Abstract excerpt

UNLABELLED: During this phase I/II study, enodolymphatic cannulae were placed in the iliac lymphatics under general anaesthesia. IL2 was then infused via this route at escalating doses until the highest tolerated dose was achieved; then, continuous infusion was maintained for 2 to 3 weeks. Seven patients with advanced cancer (3 lymphoma, 4 melanoma), resistant to all other modalities of treatment received such...

Topics

Adult
Catheterization
Female
Hemoglobins
Humans
Injections, Intralymphatic
Interleukin-2
Killer Cells, Natural
Lymphoma
Male
Melanoma
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1622738
DOI: 10.1007/BF02172654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1622738-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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