Article
Systemic IL-1 and adjuvant treatment of an experimental tumor. II. Immune status during primary tumor challenge.
Biotherapy (Dordrecht, Netherlands) - 1 Jan 1992
Kiertscher S M, Mathews H L
Abstract excerpt
In this investigation, systemic administration of interleukin-1 (IL-1) and local adjuvant therapy were shown to modify immunological parameters associated with the lymphatics draining the site of experimental tumor inoculation. These immunological parameters were shown to be modified early (within 7 days) following tumor inoculation and within the time period of IL-1 administration. IL-1 induced a marked increase...
Topics
- Adjuvants, Immunologic
- Animals
- Cytotoxicity, Immunologic
- Dose-Response Relationship, Drug
- Female
- Immunotherapy, Adoptive
- Interleukin-1
- Interleukin-2
- Lymph Nodes
- Lymphoma
- Mice