Article
Biodistribution of radiolabelled human dendritic cells injected by various routes.
European journal of nuclear medicine and molecular imaging - 1 Jul 2005
Quillien Véronique, Moisan Annick, Carsin Andre, Lesimple Thierry, Lefeuvre Claudia, Adamski Henri, Bertho Nicolas, Devillers Anne, Leberre Claudine, Toujas Louis
Abstract excerpt
PURPOSE: The purpose of this study was to investigate the biodistribution of mature dendritic cells (DCs) injected by various routes, during a cell therapy protocol. METHODS: In the context of a vaccine therapy protocol for melanoma, DCs matured with Ribomunyl and interferon-gamma were labelled with( 111)In-oxine and injected into eight patients along various routes: afferent lymphatic vessel (IL) (4 times),...
Topics
- Antigens, Bacterial
- Cancer Vaccines
- Cell Movement
- Cell Survival
- Cell Transplantation
- Cell- and Tissue-Based Therapy
- Chemokine CCL21
- Chemokines, CC
- Clinical Trials as Topic
- Dendritic Cells
- Humans
- Immunoassay
- Interferon-gamma