Article

Transdermal nanolipoplex simultaneously inhibits subcutaneous melanoma growth and suppresses systemically metastatic melanoma by activating host immunity

2022-03-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Melanoma is a malignant cancer with high rates of recurrence, metastasis, and immunosurveillance evasion. Benefit for clinical treatments of melanoma, the transdermal neoadjuvant therapy could reduce surgery region and increase immunotherapy efficacy. Using cationic lipoplex (LPPC) encapsulated doxorubicin (DOX) and carrying CpG oligodeoxynucleotide; the nano-li...

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Literature Corpus work: c4d9cda7-be3a-596a-b5d2-1d0ab1f87b51
DOI: 10.21203/rs.3.rs-1425588/v1

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