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Article

Relationship between the extent of chromosomal losses and the pattern of CpG methylation in gastric carcinomas.

Journal of Korean medical science - 1 Oct 2005

Hong Seung-Jin, Kim Young-Ho, Choi Young-Deok, Min Ki-Ouk, Choi Sang-Wook, Rhyu Mun-Gan

Abstract excerpt

The extent of unilateral chromosomal losses and the presence of microsatellite instability (MSI) have been classified into high-risk (high- and baseline-level loss) and low-risk (low-level loss and MSI) stem-line genotypes in gastric carcinomas. A unilateral genome-dosage reduction might stimulate compensation mechanism, which maintains the genomic dosage via CpG hypomethylation. A total of 120 tumor sites from...

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Source

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Identifiers

PMID: 16224153
DOI: 10.3346/jkms.2005.20.5.790
PMCID: PMC2779276

Genes

RABGEF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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