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Article

Circulating DNA in the Blood of Gastric Cancer Patients

1 Aug 2008

Abstract excerpt

The concentration of cell-free DNA and promoter methylation status of the MGMT, p15, and hMLH1 genes were analyzed by a fluorescence-based assay and methylation-specific PCR (MSP) in the blood of gastric cancer patients (n= 20) and healthy subjects (n= 22). Gastric cancer patients were characterized by an increased concentration of circulating DNA in the plasma; the amount of cell-surface-bound DNA was not...

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PMID: 18837952
DOI: 10.1196/annals.1448.009

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