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Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer

1 Jan 2004

Abstract excerpt

AIM: To explore the effect of DNA methyltransferase, demethylase and methyl-CpG binding protein MeCP2 on the expressions and methylation of hMSH2 and proto-oncogene in human gastric cancer. METHODS: Paired samples of primary gastric cancer and corresponding para-cancerous, non-cancerous gastric mucosae were obtained from surgically resected specimens of 28 patients. Transcription levels of Dnmt1, mbd2, MeCP2,...

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PMID: 15526354
DOI: 10.3748/wjg.v10.i23.3394

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