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Article

Mutational and expressional analysis of SMC2 gene in gastric and colorectal cancers with microsatellite instability.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2014

Je Eun Mi, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

Structural maintenance of chromosomes 2 (SMC2) gene encodes condensin complexes that are required for proper chromosome segregation and maintenance of chromosomal stability. Although cells with defective chromosome segregation become aneuploid and are prone to harbor chromosome instability, pathologic implications of SMC2 gene alterations are largely unknown. In a public database, we found that SMC2 gene had...

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Source

Identifiers

PMID: 24483990
DOI: 10.1111/apm.12193

Genes

SMC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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