Article
Actin-dependent regulation of the cardiac Na(+)/Ca(2+) exchanger.
American journal of physiology. Cell physiology - 1 Mar 2006
Condrescu Madalina, Reeves John P
Abstract excerpt
In the present study, the bovine cardiac Na(+)/Ca(2+) exchanger (NCX1.1) was expressed in Chinese hamster ovary cells. The surface distribution of the exchanger protein, externally tagged with the hemagglutinin (HA) epitope, was associated with underlying actin filaments in regions of cell-to-cell contact and also along stress fibers. After we treated cells with cytochalasin D, NCX1.1 protein colocalized with...
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