Article
Tissue-specific modes of Na/Ca exchanger regulation.
Annals of the New York Academy of Sciences - 1 Nov 2002
Hryshko Larry V
Abstract excerpt
Ionic regulation of Na(+)/Ca(2+) exchange describes the secondary modulating effects exerted on exchange activity by the transport substrates Na(+) and Ca(2+). These effects have been extensively characterized for the cardiac Na(+)/Ca(2+) exchanger, NCX1.1, primarily by the giant excised patch-clamp technique. Moreover, several studies have provided functional evidence for ionic regulation of Na(+)/Ca(2+)...
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