Article
Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 2005
Rebbeck Timothy R, Friebel Tara, Wagner Theresa, Lynch Henry T, Garber Judy E, Daly Mary B, Isaacs Claudine, Olopade Olufunmilayo I, Neuhausen Susan L, van 't Veer Laura, Eeles Rosalind, Evans D Gareth, Tomlinson Gail, Matloff Ellen, Narod Steven A, Eisen Andrea, Domchek Susan, Armstrong Katrina, Weber Barbara L
Abstract excerpt
PURPOSE: Bilateral prophylactic oophorectomy (BPO) is widely used for cancer risk reduction in women with BRCA1/2 mutations. Many premenopausal women choose to take hormone replacement therapy (HRT) after undergoing BPO to abrogate immediate symptoms of surgically-induced menopause. Thus, we eval...
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