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Article

Short-term Impact of Hormone Replacement Therapy on Risk of Breast Cancer in BRCA Mutation Carriers: A Nationwide Study in South Korea.

Cancer research and treatment - 1 Jan 2024

Kim Hye Yeon, Park Jisoo, Moon Seok Joo, Jeong Sohyeon, Hong Jin Hwa, Lee Jae Kwan, Cho Geum Joon, Cho Hyun-Woong

Abstract excerpt

PURPOSE: BRCA1/2 mutations are well-known risk factors for breast and ovarian cancers in women. Risk-reducing salpingo-oophorectomy (RRSO) is the standard treatment for preventing ovarian cancer with BRCA mutations. Postmenopausal syndrome (symptoms after RRSO can be alleviated by hormone replacement therapy (HRT); however, the use of HRT in carriers of BRCA mutations has been controversial because of the concern...

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Identifiers

PMID: 37591780
DOI: 10.4143/crt.2023.653
PMCID: PMC10789953

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