Nuclear-mitochondrial epistasis and drosophila aging: introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds.

Abstract excerpt

Under the mitochondrial theory of aging, physiological decline with age results from the accumulated cellular damage produced by reactive oxygen species generated during electron transport in the mitochondrion. A large body of literature has documented age-specific declines in mitochondrial function that are consistent with this theory, but relatively few studies have been able to distinguish cause from...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Nucleus
• Share to Crosses, Genetic
• Share to Cytoplasm