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Article

Drosophila as a Model System to Investigate the Effects of Mitochondrial Variation on Innate Immunity.

Frontiers in immunology - 1 Jan 2020

Salminen Tiina S, Vale Pedro F

Abstract excerpt

Understanding why the response to infection varies between individuals remains one of the major challenges in immunology and infection biology. A substantial proportion of this heterogeneity can be explained by individual genetic differences which result in variable immune responses, and there are many examples of polymorphisms in nuclear-encoded genes that alter immunocompetence. However, how immunity is...

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Identifiers

PMID: 32269576
DOI: 10.3389/fimmu.2020.00521
PMCID: PMC7109263

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