Article
Drosophila simulans as a novel model for studying mitochondrial metabolism and aging.
Experimental gerontology - 1 Oct 2005
Ballard J William O
Abstract excerpt
Mitochondria generate much of the cellular energy through the process of oxidative phosphorylation (OXPHOS). OXPHOS function may be affected by a mutation in any of the mitochondrial (mt) DNA encoded genes and/or nuclear encoded genes that produce proteins imported into the mitochondrion that form (or assemble) the five complexes located on the inner mitochondrial membrane. Decreasing mitochondrial OXPHOS...
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