Article
Comparative analysis of mitochondrial genotype and aging.
Annals of the New York Academy of Sciences - 1 Oct 2007
Ballard J William O, Katewa Subhash D, Melvin Richard G, Chan Grace
Abstract excerpt
A common feature across all animals, including humans, is that mitochondrial bioenergetics is linked to oxidative stress, but the nature of these relationships with survival is yet to be properly defined. In this study we included 12 Drosophila simulans isofemale lines: four of each distinct mtDNA haplogroup (siI, -II, and -III). First, we investigated sequence variation in six mtDNA and 13 nuclear encoded genes...
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