Article
Inactivation of Galpha(z) causes disassembly of the Golgi apparatus.
Journal of cell science - 1 Dec 2002
Nagahama Masami, Usui Shihomi, Shinohara Takashi, Yamaguchi Tomohiro, Tani Katsuko, Tagaya Mitsuo
Abstract excerpt
We showed previously that overexpression of the alpha subunit of G(z) or G(i2) suppresses nordihydroguaiaretic acid-induced Golgi disassembly. To determine whether the active form of Galpha is required to maintain the structure of the Golgi apparatus, we examined the effects of a series of Galpha GAPs, regulators of G protein signaling (RGS) proteins, on the Golgi structure. Expression of RGSZ1 or RGSZ2, both of...
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