Article
Detection and automatic repair of nucleotide base-pair mutations by coherent light.
Journal of the American Chemical Society - 19 Oct 2005
Thanopulos Ioannis, Shapiro Moshe
Abstract excerpt
We show that phase-coherent optical techniques allow for the detection and automatic repair of mutations in nucleotide pairs. We demonstrate computationally that there is a laser pulse sequence that can detect the occurrence of a mutation caused by a double proton transfer between hydrogen-bonded nucleotide pairs and automatically repair it by converting the mutated nucleotide pair to the nonmutated one. The...
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