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The Transcription Machinery and the Driving Force of the Transcriptional Molecular Condensate: The Role of Phosphates

2025-06-30

Abstract excerpt

The dynamic phosphorylation of the human RNA Pol II CTD establishes a code applicable to all eukaryotic transcription processes. However, the ability of these specific post-translational modifications to convey molecular signals through structural changes remains unclear. We previously explained that each gene can be modeled as a combination of n circuits connected in parallel. RNA Pol II accesses these circuits a...

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Identifiers and source

Literature Corpus work
f336aa8d-3415-56b6-b938-6a30dfa706cd
DOI
10.20944/preprints202506.2469.v1
Open publication

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