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Article

Structural basis for glycogen recognition by AMP-activated protein kinase.

Structure (London, England : 1993) - 1 Oct 2005

Polekhina Galina, Gupta Abhilasha, van Denderen Bryce J W, Feil Susanne C, Kemp Bruce E, Stapleton David, Parker Michael W

Abstract excerpt

AMP-activated protein kinase (AMPK) coordinates cellular metabolism in response to energy demand as well as to a variety of stimuli. The AMPK beta subunit acts as a scaffold for the alpha catalytic and gamma regulatory subunits and targets the AMPK heterotrimer to glycogen. We have determined the structure of the AMPK beta glycogen binding domain in complex with beta-cyclodextrin. The structure reveals a...

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Identifiers

PMID: 16216577
DOI: 10.1016/j.str.2005.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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