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Article

Advances in the molecular biology of malignant mesothelioma.

Acta medica Okayama - 1 Feb 2008

Toyooka Shinichi, Kishimoto Takumi, Date Hiroshi

Abstract excerpt

Malignant mesothelioma (MM) is a highly aggressive tumor with a dismal prognosis. The incidence of MM is increasing as a result of widespread exposure to asbestos. As for the molecular alterations that occur in MM, chromosome alterations including homo-deletion of the P16 and P14 genes located in the 9p21 are well known. Mutations are rare in the P53 and Ras genes, which are frequently present in epithelial solid...

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Identifiers

PMID: 18323865
DOI: 10.18926/AMO/30990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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